A rapid and efficient platform for antiviral crRNA screening using CRISPR-Cas13a-based nucleic acid detection

IntroductionRapid and high-throughput screening of antiviral clustered regularly interspaced short palindromic repeat (CRISPR) RNAs (crRNAs) is urgently required for the CRISPR-Cas13a antiviral system. Based on the same principle, we established an efficient screening platform for antiviral crRNA th...

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Bibliographic Details
Main Authors: Lan Yang, Youcui Zhang, Wenyanbo Yi, Xue Dong, Mengwei Niu, Yingjie Song, Yao Han, Hao Li, Yansong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116230/full