<i>PPARG</i> Hypermethylation as the First Epigenetic Modification in Newly Onset Insulin Resistance in Human Adipocytes

Insulin acts by binding with a specific receptor called an insulin receptor (INSR), ending up with glucose transporter activation and glucose uptake. Insulin resistance (IR) is a state when the physiological amount of insulin is not sufficient to evoke proper action, i.e., glucose uptake. Epigenetic...

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Bibliographic Details
Main Authors: Małgorzata Małodobra-Mazur, Aneta Cierzniak, Krzysztof Kaliszewski, Tadeusz Dobosz
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/6/889