FAK family kinases: The Yin and Yang of cancer cell invasiveness

FAK family kinases: The Yin and Yang of cancer cell invasiveness

Proline-rich tyrosine kinase 2 (PYK2, also known as Pyk2) and its closely related focal adhesion kinase (FAK) modulate cancer cell invasion by coordinating the balance between focal adhesion-mediated migration and invadopodia-dependent extracellular matrix invasion. Our recent findings present Pyk2...

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Bibliographic Details
Main Authors: Alessandro Genna, Hava Gil-Henn
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:Molecular & Cellular Oncology
Subjects:
fak
pyk2
focal adhesions
invadopodia
invasion
migration
Online Access:http://dx.doi.org/10.1080/23723556.2018.1449584

Internet

http://dx.doi.org/10.1080/23723556.2018.1449584

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