The IMPACT OF SUPEROXIDE DISMUTASE GENETIC POLYMORPHISM (SOD2 VAL16ALA) AND SUPEROXIDE DISMUTASE LEVEL ON DISEASE SEVERITY IN A COHORT OF EGYPTIAN SICKLE CELL DISEASE PATIENTS IN EGYPT

The IMPACT OF SUPEROXIDE DISMUTASE GENETIC POLYMORPHISM (SOD2 VAL16ALA) AND SUPEROXIDE DISMUTASE LEVEL ON DISEASE SEVERITY IN A COHORT OF EGYPTIAN SICKLE CELL DISEASE PATIENTS IN EGYPT

Background: Oxidative stress plays a pivotal role in the pathophysiology of sickle cell disease (SCD) and its associated disease complications. Superoxide Dismutases (SODs) are protective enzymes against oxidative stress. SOD2 deficiency results in the accumulation of oxidized red cell proteins, in...

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Detalhes bibliográficos
Main Authors: Mervat Khorshied, Iman Shaheen, Yasmeen Selim, Asmaa Elshahawy, Ilham Youssry
Formato: Artigo
Idioma:English
Publicado em: PAGEPress Publications 2022-04-01
Colecção:Mediterranean Journal of Hematology and Infectious Diseases
Assuntos:
SOD2, rs4880, SCD, Egypt
Acesso em linha:https://www.mjhid.org/index.php/mjhid/article/view/4926

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