C1q/Tumor Necrosis Factor–Related Protein‐9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose‐Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase

C1q/Tumor Necrosis Factor–Related Protein‐9 Is a Novel Vasculoprotective Cytokine That Restores High Glucose‐Suppressed Endothelial Progenitor Cell Functions by Activating the Endothelial Nitric Oxide Synthase

Background This study investigated whether gCTRP9 (globular C1q/tumor necrosis factor–related protein‐9) could restore high‐glucose (HG)‐suppressed endothelial progenitor cell (EPC) functions by activating the endothelial nitric oxide synthase (eNOS). Methods and Results EPCs were treated with HG (2...

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Bibliographic Details
Main Authors: Qingsong Hu, Wan Qu, Tao Zhang, Jianyi Feng, Xiaobian Dong, Ruqiong Nie, Junyu Chen, Xiaoqing Wang, Changnong Peng, Xiao Ke
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
C1q/TNF‐related protein‐9
diabetes
endothelial nitric oxide synthase (eNOS)
endothelial progenitor cells
high glucose
reendothelialization
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.030054

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https://www.ahajournals.org/doi/10.1161/JAHA.123.030054

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