Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

Cisplatin protects mice from challenge of Cryptococcus neoformans by targeting the Prp8 intein

ABSTRACTThe Prp8 intein is one of the most widespread eukaryotic inteins, present in important pathogenic fungi, including Cryptococcus and Aspergillus species. Because the processed Prp8 carries out essential and non-redundant cellular functions, a Prp8 intein inhibitor is a mechanistically novel a...

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Podrobná bibliografie
Hlavní autoři: Zhong Li, Bin Fu, Cathleen M. Green, Binbin Liu, Jing Zhang, Yuekun Lang, Sudha Chaturvedi, Marlene Belfort, Guojian Liao, Hongmin Li
Médium: Článek
Jazyk:English
Vydáno: Taylor & Francis Group 2019-01-01
Edice:Emerging Microbes and Infections
Témata:
Cisplatin
antifungal
Cryptococcus
Prp8 intein
mouse model
On-line přístup:https://www.tandfonline.com/doi/10.1080/22221751.2019.1625727

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2019.1625727

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