HIV-associated vaginal microbiome and inflammation predict spontaneous preterm birth in Zambia

Abstract A Lactobacillus-deficient, anaerobe-rich vaginal microbiome has been associated with local inflammation and spontaneous preterm birth (sPTB), but few studies have assessed this association in the setting of HIV. We performed metagenomic sequencing and inflammatory marker assays on vaginal s...

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Bibliographic Details
Main Authors: Joan T. Price, Bellington Vwalika, Michael France, Jacques Ravel, Bing Ma, Humphrey Mwape, Katelyn J. Rittenhouse, Kristina De Paris, Marcia Hobbs, Julie A. Nelson, Margaret P. Kasaro, Elizabeth M. Stringer, Jeffrey S. A. Stringer
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12424-w