Envelope determinants of equine lentiviral vaccine protection.

Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection associated with Env variation have yet to be dete...

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Bibliographic Details
Main Authors: Jodi K Craigo, Corin Ezzelarab, Sheila J Cook, Liu Chong, David Horohov, Charles J Issel, Ronald C Montelaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3682429?pdf=render