Taurine reduces microglia activation in the brain of aged senescence-accelerated mice by increasing the level of TREM2

Taurine reduces microglia activation in the brain of aged senescence-accelerated mice by increasing the level of TREM2

Abstract Alzheimer’s disease (AD), a chronic neurodegenerative disorder, is the leading cause of dementia. Over-activated microglia is related to amyloid-beta (Aβ) and phosphorylated tau (phospho-tau) accumulation in the AD brain. Taurine is an amino acid with multiple physiological functions includ...

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Bibliographic Details
Main Authors: Sharif Ahmed, Ning Ma, Jun Kawanokuchi, Keiya Matsuoka, Shinji Oikawa, Hatasu Kobayashi, Yusuke Hiraku, Mariko Murata
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57973-4

Internet

https://doi.org/10.1038/s41598-024-57973-4

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