Lipofuscin-like autofluorescence within microglia and its impact on studying microglial engulfment

Abstract Engulfment of cellular material and proteins is a key function for microglia, a resident macrophage of the central nervous system (CNS). Among the techniques used to measure microglial engulfment, confocal light microscopy has been used the most extensively. Here, we show that autofluoresce...

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Bibliographic Details
Main Authors: Jacob M. Stillman, Francisco Mendes Lopes, Jing-Ping Lin, Kevin Hu, Daniel S. Reich, Dorothy P. Schafer
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42809-y