Effect of Pressure on Thermal Stability of G-Quadruplex DNA and Double-Stranded DNA Structures

Pressure is a thermodynamic parameter that can induce structural changes in biomolecules due to a volumetric decrease. Although most proteins are denatured by pressure over 100 MPa because they have the large cavities inside their structures, the double-stranded structure of DNA is stabilized or des...

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Bibliographic Details
Main Authors: Shuntaro Takahashi, Naoki Sugimoto
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/11/13297