Synthesis and Biological Evaluation of N-Alkoxyphenyl-3-hydroxynaphthalene-2-carboxanilides

Synthesis and Biological Evaluation of N-Alkoxyphenyl-3-hydroxynaphthalene-2-carboxanilides

A series of fifteen new N-alkoxyphenylanilides of 3-hydroxynaphthalene-2-carboxylic acid was prepared and characterized. Primary in vitro screening of the synthesized compounds was performed against Staphylococcus aureus, three methicillin-resistant S. aureus strains, Mycobacterium tuberculosis H37R...

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Bibliographic Details
Main Authors: Tomas Gonec, Iveta Zadrazilova, Eoghan Nevin, Tereza Kauerova, Matus Pesko, Jiri Kos, Michal Oravec, Peter Kollar, Aidan Coffey, Jim O'Mahony, Alois Cizek, Katarina Kralova, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Molecules
Subjects:
hydroxynaphthalene-2-carboxanilides
in vitro antibacterial activity
in vitro antimycobacterial activity
in vitro cytotoxicity
photosynthetic electron transport inhibition
structure-activity relationships
Online Access:http://www.mdpi.com/1420-3049/20/6/9767

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http://www.mdpi.com/1420-3049/20/6/9767

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