Long noncoding RNAs: p53's secret weapon in the fight against cancer?

p53 regulates the expression of hundreds of genes. Recent surprising observations indicate that no single protein-coding gene controls the tumor suppressor effects of p53. This raises the possibility that a subset of these genes, regulated by a p53-induced long noncoding RNA (lncRNA), could control...

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Bibliographic Details
Main Authors: Emily Dangelmaier, Sarah B Lazar, Ashish Lal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000143