Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.

Histone deacetylase 8 is required for centrosome cohesion and influenza A virus entry.

Influenza A virus (IAV) enters host cells by endocytosis followed by acid-activated penetration from late endosomes (LEs). Using siRNA silencing, we found that histone deacetylase 8 (HDAC8), a cytoplasmic enzyme, efficiently promoted productive entry of IAV into tissue culture cells, whereas HDAC1 s...

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Bibliographic Details
Main Authors: Yohei Yamauchi, Heithem Boukari, Indranil Banerjee, Ivo F Sbalzarini, Peter Horvath, Ari Helenius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046129/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22046129/pdf/?tool=EBI

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