Nicotinamide and calcipotriol counteract UVB-induced photoaging on primary human dermal fibroblasts

Nicotinamide and calcipotriol counteract UVB-induced photoaging on primary human dermal fibroblasts

Background: Photoaging is mainly caused by ultraviolet radiations inasmuch they can damage the DNA, trigger ROS production, and activate p53/p21 pathway, which cause cell cycle arrest and senescence. The accumulation of senescent cells within the dermis contributes to tissue deregulation and skin ca...

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Bibliographic Details
Main Authors: Lara Camillo, Laura Cristina Gironi, Elia Esposto, Elisa Zavattaro, Paola Savoia
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Photochemistry and Photobiology
Subjects:
Ultraviolet
Dermal fibroblasts
Photoaging
Nicotinamide
Calcipotriol
Senescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2666469022000513

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http://www.sciencedirect.com/science/article/pii/S2666469022000513

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