In Vitro Affinity Maturation of Nanobodies against Mpox Virus A29 Protein Based on Computer-Aided Design

In Vitro Affinity Maturation of Nanobodies against Mpox Virus A29 Protein Based on Computer-Aided Design

Mpox virus (MPXV), the most pathogenic zoonotic orthopoxvirus, caused worldwide concern during the SARS-CoV-2 epidemic. Growing evidence suggests that the MPXV surface protein A29 could be a specific diagnostic marker for immunological detection. In this study, a fully synthetic phage display librar...

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Bibliographic Details
Main Authors: Haiyang Yu, Guanchao Mao, Zhipeng Pei, Jinfeng Cen, Wenqi Meng, Yunqin Wang, Shanshan Zhang, Songling Li, Qingqiang Xu, Mingxue Sun, Kai Xiao
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
MPXV
A29 protein
nanobody
in vitro affinity maturation
Online Access:https://www.mdpi.com/1420-3049/28/19/6838

Internet

https://www.mdpi.com/1420-3049/28/19/6838

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