Cell type-specific calcium imaging of central sensitization in mouse dorsal horn

Altered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization.

Bibliographic Details
Main Authors: Charles Warwick, Joseph Salsovic, Junichi Hachisuka, Kelly M. Smith, Tayler D. Sheahan, Haichao Chen, James Ibinson, H. Richard Koerber, Sarah E. Ross
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32608-2