Cell type-specific calcium imaging of central sensitization in mouse dorsal horn
Altered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32608-2 |
| _version_ | 1811274816024477696 |
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| author | Charles Warwick Joseph Salsovic Junichi Hachisuka Kelly M. Smith Tayler D. Sheahan Haichao Chen James Ibinson H. Richard Koerber Sarah E. Ross |
| author_facet | Charles Warwick Joseph Salsovic Junichi Hachisuka Kelly M. Smith Tayler D. Sheahan Haichao Chen James Ibinson H. Richard Koerber Sarah E. Ross |
| author_sort | Charles Warwick |
| collection | DOAJ |
| description | Altered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization. |
| first_indexed | 2024-04-12T23:27:05Z |
| format | Article |
| id | doaj.art-80ac351424da470497cb041b61dfcedc |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T23:27:05Z |
| publishDate | 2022-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-80ac351424da470497cb041b61dfcedc2022-12-22T03:12:23ZengNature PortfolioNature Communications2041-17232022-09-0113111710.1038/s41467-022-32608-2Cell type-specific calcium imaging of central sensitization in mouse dorsal hornCharles Warwick0Joseph Salsovic1Junichi Hachisuka2Kelly M. Smith3Tayler D. Sheahan4Haichao Chen5James Ibinson6H. Richard Koerber7Sarah E. Ross8Department of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Anesthesiology, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghDepartment of Neurobiology and the Pittsburgh Center for Pain Research, University of PittsburghAltered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization.https://doi.org/10.1038/s41467-022-32608-2 |
| spellingShingle | Charles Warwick Joseph Salsovic Junichi Hachisuka Kelly M. Smith Tayler D. Sheahan Haichao Chen James Ibinson H. Richard Koerber Sarah E. Ross Cell type-specific calcium imaging of central sensitization in mouse dorsal horn Nature Communications |
| title | Cell type-specific calcium imaging of central sensitization in mouse dorsal horn |
| title_full | Cell type-specific calcium imaging of central sensitization in mouse dorsal horn |
| title_fullStr | Cell type-specific calcium imaging of central sensitization in mouse dorsal horn |
| title_full_unstemmed | Cell type-specific calcium imaging of central sensitization in mouse dorsal horn |
| title_short | Cell type-specific calcium imaging of central sensitization in mouse dorsal horn |
| title_sort | cell type specific calcium imaging of central sensitization in mouse dorsal horn |
| url | https://doi.org/10.1038/s41467-022-32608-2 |
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