mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2

mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2

After myocardial injury, cardiac fibroblasts (CFs) differentiate into myofibroblasts, which express and secrete extracellular matrix (ECM) components for myocardial repair, but also promote myocardial fibrosis. Recombinant fibroblast growth factor 2 (FGF2) protein drug with low molecular weight can...

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Bibliographic Details
Main Authors: Changye Sun, Mengru Bai, Yangyang Jia, Xiangqin Tian, Yonglong Guo, Xinhui Xu, Zhikun Guo
Format: Article
Language:English
Published: PeerJ Inc. 2023-07-01
Series:PeerJ
Subjects:
Fibroblast growth factor 2 (FGF2)
Cardiac fibroblasts (CFs) activation
mRNA sequencing
Extracellular matrix (ECM) organization
Actin filament organization
Online Access:https://peerj.com/articles/15736.pdf

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https://peerj.com/articles/15736.pdf

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