Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis

Benzoic Acid Derivatives as Prodrugs for the Treatment of Tuberculosis

One interesting approach to fight tuberculosis is the use of prodrugs that often have shown improved biological activities over drugs with poor absorption or difficulty to cross membranes. Previous studies demonstrate that weak acids such as benzoic acid, present antimycobacterial activity. Moreover...

Full description

Bibliographic Details
Main Authors: João P. Pais, Marta Magalhães, Olha Antoniuk, Ivete Barbosa, Raquel Freire, David Pires, Emília Valente, Bernard Testa, Elsa Anes, Luis Constantino
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceuticals
Subjects:
benzoates
nitrobenzoates
tuberculosis
prodrugs
esterases
mycobacteria
Online Access:https://www.mdpi.com/1424-8247/15/9/1118

Internet

https://www.mdpi.com/1424-8247/15/9/1118

Similar Items