A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction

A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction

The transplantation of ex vivo expanded limbal epithelial progenitor cells (LEPCs) on amniotic membrane or fibrin gel is an established therapeutic strategy to regenerate the damaged corneal surface in patients with limbal stem cell deficiency (LSCD), but the long-term success rate is restricted. A...

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Bibliographic Details
Main Authors: Naresh Polisetti, Benjamin Roschinski, Ursula Schlötzer-Schrehardt, Philip Maier, Günther Schlunck, Thomas Reinhard
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
decellularization
limbal tissue engineering
limbal transplantation
ex vivo transplantation
recellularization
decellularized limbal tissue
Online Access:https://www.mdpi.com/1422-0067/22/18/10067

Internet

https://www.mdpi.com/1422-0067/22/18/10067

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