The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

Objective: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...

Full description

Bibliographic Details
Main Authors: Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Molecular Metabolism
Subjects:
Diabetes
Glucose homeostasis
Pancreatic islet
Transcription factor
Co-regulator
Gene regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001199

Internet

http://www.sciencedirect.com/science/article/pii/S2212877823001199

Similar Items