Mitochondria, a Key Target in Amyotrophic Lateral Sclerosis Pathogenesis

Mitochondria, a Key Target in Amyotrophic Lateral Sclerosis Pathogenesis

Mitochondrial dysfunction occurs in numerous neurodegenerative diseases, particularly amyotrophic lateral sclerosis (ALS), where it contributes to motor neuron (MN) death. Of all the factors involved in ALS, mitochondria have been considered as a major player, as secondary mitochondrial dysfunction...

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Bibliographic Details
Main Authors: Emmanuelle C. Genin, Mélanie Abou-Ali, Véronique Paquis-Flucklinger
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
mitochondria
amyotrophic lateral sclerosis
motor neuron disease
frontotemporal dementia
ALS genes
<i>CHCHD10</i>
Online Access:https://www.mdpi.com/2073-4425/14/11/1981

Internet

https://www.mdpi.com/2073-4425/14/11/1981

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