PD-1 blockade potentiates neoadjuvant chemotherapy in NSCLC via increasing CD127+ and KLRG1+ CD8 T cells

PD-1 blockade potentiates neoadjuvant chemotherapy in NSCLC via increasing CD127+ and KLRG1+ CD8 T cells

Abstract The combination of PD-1 blockade with neoadjuvant chemotherapy (NAC) has achieved unprecedented clinical success in non-small cell lung cancer (NSCLC) compared to NAC alone, but the underlying mechanisms by which PD-1 blockade augments the effects of chemotherapy remain incompletely elucida...

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Bibliographic Details
Main Authors: Zhenzhen Hui, Yulin Ren, Dong Zhang, Yulong Chen, Wenwen Yu, Jie Cao, Liang Liu, Tao Wang, Shanshan Xiao, Liuqing Zheng, Yue Pu, Feng Wei, Jian You, Xiubao Ren
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00384-x

Internet

https://doi.org/10.1038/s41698-023-00384-x

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