Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum

Abstract Cryptosporidium parvum is an obligate intracellular parasite with a highly reduced mitochondrion that lacks the tricarboxylic acid cycle and the ability to generate ATP, making the parasite reliant on glycolysis. Genetic ablation experiments demonstrated that neither of the two putative glu...

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Bibliographic Details
Main Authors: Rui Xu, Wandy L. Beatty, Valentin Greigert, William H. Witola, L. David Sibley
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-44696-3