Former smoking associated with epigenetic modifications in human granulosa cells among women undergoing assisted reproduction

Abstract Smoking exposure during adulthood can disrupt oocyte development in women, contributing to infertility and possibly adverse birth outcomes. Some of these effects may be reflected in epigenome profiles in granulosa cells (GCs) in human follicular fluid. We compared the epigenetic modificatio...

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Bibliographic Details
Main Authors: Ziyin Tang, Audrey J. Gaskins, Robert B. Hood, Jennifer B. Ford, Russ Hauser, Alicia K. Smith, Todd M. Everson
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-54957-2