Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease

Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease

IntroductionDue to a lack of spatial-temporal resolution at the single cell level, the etiologies of the bone dysfunction caused by diseases such as normal aging, osteoporosis, and the metabolic bone disease associated with chronic kidney disease (CKD) remain largely unknown.MethodsTo this end, flow...

Full description

Bibliographic Details
Main Authors: Rafiou Agoro, Intawat Nookaew, Megan L. Noonan, Yamil G. Marambio, Sheng Liu, Wennan Chang, Hongyu Gao, Lainey M. Hibbard, Corinne E. Metzger, Daniel Horan, William R. Thompson, Xiaoling Xuei, Yunlong Liu, Chi Zhang, Alexander G. Robling, Lynda F. Bonewald, Jun Wan, Kenneth E. White
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
bone
scRNAseq
osteoblasts
osteocytes
chronic kidney disease
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1063083/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1063083/full

Similar Items