Conditional Deletion of the V-ATPase a2-Subunit Disrupts Intrathymic T Cell Development

Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nucleus, shaping a distinct transcriptional program t...

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Detalles Bibliográficos
Autores principales: Theodore V. Peterson, Mukesh K. Jaiswal, Kenneth D. Beaman, Joseph M. Reynolds
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2019-08-01
Colección:Frontiers in Immunology
Materias:
Acceso en línea:https://www.frontiersin.org/article/10.3389/fimmu.2019.01911/full