Conditional Deletion of the V-ATPase a2-Subunit Disrupts Intrathymic T Cell Development
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nucleus, shaping a distinct transcriptional program t...
Autores principales: | , , , |
---|---|
Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019-08-01
|
Colección: | Frontiers in Immunology |
Materias: | |
Acceso en línea: | https://www.frontiersin.org/article/10.3389/fimmu.2019.01911/full |