Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction

Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction

Objectives: Glucagon-like peptide-1 receptor (GLP-1R) agonists reduce the rates of major cardiovascular events, including myocardial infarction in people with type 2 diabetes, and decrease infarct size while preserving ventricular function in preclinical studies. Nevertheless, the precise cellular s...

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Bibliographic Details
Main Authors: Brent A. McLean, Chi Kin Wong, M Golam Kabir, Daniel J. Drucker
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Heart
Myocardial infarction
Diabetes
Obesity
Peptides
G protein coupled receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822002101

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http://www.sciencedirect.com/science/article/pii/S2212877822002101

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