TissueGrinder, a novel technology for rapid generation of patient-derived single cell suspensions from solid tumors by mechanical tissue dissociation

TissueGrinder, a novel technology for rapid generation of patient-derived single cell suspensions from solid tumors by mechanical tissue dissociation

IntroductionRecent advances hold promise of making personalized medicine a step closer to implementation in clinical settings. However, traditional sample preparation methods are not robust and reproducible. In this study, the TissueGrinder, a novel mechanical semi-automated benchtop device, which c...

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Bibliographic Details
Main Authors: Stefan Scheuermann, Jonas M. Lehmann, Ramkumar Ramani Mohan, Christoph Reißfelder, Felix Rückert, Jens Langejürgen, Prama Pallavi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
single cell isolation methods
mechanical dissociation
enzyme free
tumor-derived cell culture
personalized medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.721639/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.721639/full

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