Anti-inflammatory Activity and PGE2 Inhibitory Properties of Novel Phenylcarbamoylmethyl Ester-Containing Compounds

A variety of 4-(un)substituted phenylcarbamoyl methyl ester-containing compounds 3a-d, 5a-d and 7a-d were synthesized via reaction in N,N-dimethylformamide of (un)substituted chloroacetanilides 2a-d with the potassium salts of ibuprofen (1), naproxen (4) and N-acetylanthranilic acid (6). Moreover, o...

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Bibliographic Details
Main Authors: Nagwa Abdel-Gawad, Hanan Georgey, Flora Barsoum
Format: Article
Language:English
Published: MDPI AG 2009-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/14/2/667/