A novel thinking: DDR axis refines the classification of ccRCC with distinctive prognosis, multi omics landscape and management strategy

A novel thinking: DDR axis refines the classification of ccRCC with distinctive prognosis, multi omics landscape and management strategy

BackgroundDNA damage response and repair (DDR) related signatures play an important role in maintaining genome stability and other biological processes. It also affects the occurrence, development, and treatment of cancer. However, in renal cell carcinoma (RCC), especially clear cell renal carcinoma...

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Bibliographic Details
Main Authors: Aimin Jiang, Jiaao Song, Xiao Fang, Yu Fang, Zheng Wang, Bing Liu, Zhenjie Wu, Le Qu, Peng Luo, Linhui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Public Health
Subjects:
renal cell carcinoma
DNA damage response
molecular subtypes
multi-omics
DDX1
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.1029509/full

Internet

https://www.frontiersin.org/articles/10.3389/fpubh.2022.1029509/full

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