Oligosaccharides from Sargassum thunbergii inhibit osteoclast differentiation via regulation of IRF-8 signaling

Oligosaccharides from Sargassum thunbergii inhibit osteoclast differentiation via regulation of IRF-8 signaling

Osteoporosis (OP) is a systemic bone degenerative disease characterized by low bone mass and deteriorated microarchitecture of bone tissue, causing high morbidity and mortality rates. Bone resorption by overactivated osteoclasts (OCs) is the main cause of osteoporosis. Glucuronomannan and its oligom...

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Bibliographic Details
Main Authors: Weihua Jin, Fen Chen, Qiufu Fang, Genxiang Mao, Yizhong Bao
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Experimental Gerontology
Subjects:
Osteoporosis
Glucuronomannan
Oligosaccharides
Osteoclast
NF-κB
IRF-8
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556522003667

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http://www.sciencedirect.com/science/article/pii/S0531556522003667

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