Identifying the immune interactions underlying HLA class I disease associations

Identifying the immune interactions underlying HLA class I disease associations

Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci. These genetic associations provide a powerful opportunity for understanding the etiology of human disease. HLA class I associations are often...

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Bibliographic Details
Main Authors: Bisrat J Debebe, Lies Boelen, James C Lee, IAVI Protocol C Investigators, Chloe L Thio, Jacquie Astemborski, Gregory Kirk, Salim I Khakoo, Sharyne M Donfield, James J Goedert, Becca Asquith
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
HLA
GWAS
CD8 T cell
natural killer cell
disease association
immunogenetics
Online Access:https://elifesciences.org/articles/54558

Internet

https://elifesciences.org/articles/54558

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