In vivo dose–response analysis to acetylcholine: pharmacodynamic assessment by polarized reflectance spectroscopy

Abstract Transdermal iontophoresis offers an in vivo alternative to the strain-gauge model for measurement of vascular function but is limited due to lack of technical solutions for outcome assessment. The aims of this study were to, after measurement by polarized reflectance spectroscopy (PRS), use...

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Bibliographic Details
Main Authors: Joakim Henricson, Folke Sjöberg, Fredrik Iredahl, Tomas Strömberg, Daniel Wilhelms
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-10617-x