Inhibitory Effect of Andrographis paniculata Lactone on Staphylococcus aureus α-Hemolysin

Inhibitory Effect of Andrographis paniculata Lactone on Staphylococcus aureus α-Hemolysin

We investigated the effect of andrographolide (AP) on the hemolytic capacity of Staphylococcus aureus (S. aureus) isolated from our region. AP is a labdane diterpenoid isolated from the stem and leaves of Andrographis paniculata. The hla gene from 234 S. aureus strains and the quality control standa...

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Bibliographic Details
Main Authors: Xin Wang, Qiang Ma, Xiaohao Niu, Zhu Liu, Xinyun Kang, Yanni Mao, Na Li, Guiqin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
Staphylococcus aureus
toxicity factors
α-hemolysin
andrographolide
bioinformatics
molecular simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.891943/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.891943/full

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