Structural insights into Saccharomyces cerevisiae Msh4-Msh5 complex function using homology modeling.

The Msh4-Msh5 protein complex in eukaryotes is involved in stabilizing Holliday junctions and its progenitors to facilitate crossing over during Meiosis I. These functions of the Msh4-Msh5 complex are essential for proper chromosomal segregation during the first meiotic division. The Msh4/5 proteins...

Full description

Bibliographic Details
Main Authors: Ramaswamy Rakshambikai, Narayanaswamy Srinivasan, Koodali Thazath Nishant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828297?pdf=render