ASC-J9 Blocks Cell Proliferation and Extracellular Matrix Production of Keloid Fibroblasts through Inhibiting STAT3 Signaling

ASC-J9 Blocks Cell Proliferation and Extracellular Matrix Production of Keloid Fibroblasts through Inhibiting STAT3 Signaling

Keloids are a fibrotic skin disorder caused by abnormal wound healing and featuring the activation and expansion of fibroblasts beyond the original wound margin. Signal transducer and activator of transcription 3 (STAT3) has been found to mediate the biological functions of keloid fibroblasts (KFs)....

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Bibliographic Details
Main Authors: Yi-Kai Hong, Chen-Han Wu, Yu-Chen Lin, Yu-Lun Huang, Kuo-Shu Hung, Tsung-Pin Pai, Yen-Ting Liu, Tzu-Chi Chen, Hardy Chan, Chao-Kai Hsu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
keloid fibroblast
ASC-J9
STAT3
cell proliferation
ECM production
Online Access:https://www.mdpi.com/1422-0067/23/10/5549

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https://www.mdpi.com/1422-0067/23/10/5549

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