Homeobox D9 drives the malignant phenotypes and enhances the Programmed death ligand-1 expression in non-small cell lung cancer cells via binding to Angiopoietin-2 promoter

Homeobox D9 drives the malignant phenotypes and enhances the Programmed death ligand-1 expression in non-small cell lung cancer cells via binding to Angiopoietin-2 promoter

Abstract Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Homeobox D9 (HOXD9), a member of the HOX family of transcription factors, plays a driver role in development of multiple cancers. Angiopoietin-2 (ANGPT2) is reportedly to facilitate angiogenesis, grow...

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Bibliographic Details
Main Authors: Jiabei He, Mengjia Jiang, Jing Liu, Ruiping Zhu, Weipeng Lv, Ruiqing Lian, Yang Yang, Ruoyu Wang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:World Journal of Surgical Oncology
Subjects:
Homeobox D9
Angiopoietin-2
Non-small cell lung cancer
Malignant behavior
Programmed death ligand-1
Online Access:https://doi.org/10.1186/s12957-023-02969-z

Internet

https://doi.org/10.1186/s12957-023-02969-z

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