Predicting the Kinetic Coordination of Immune Response Dynamics in SARS-CoV-2 Infection: Implications for Disease Pathogenesis

Predicting the Kinetic Coordination of Immune Response Dynamics in SARS-CoV-2 Infection: Implications for Disease Pathogenesis

A calibrated mathematical model of antiviral immune response to SARS-CoV-2 infection is developed. The model considers the innate and antigen-specific responses to SARS-CoV-2 infection. Recently published data sets from human challenge studies with SARS-CoV-2 were used for parameter evaluation. The...

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Bibliographic Details
Main Authors: Dmitry Grebennikov, Antonina Karsonova, Marina Loguinova, Valentina Casella, Andreas Meyerhans, Gennady Bocharov
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Mathematics
Subjects:
SARS-CoV-2 infection
innate immune response
antigen-specific immune response
kinetic coordination
mathematical model
pathogenesis
Online Access:https://www.mdpi.com/2227-7390/10/17/3154

Internet

https://www.mdpi.com/2227-7390/10/17/3154

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