Supraphysiological effects of pancreatic polypeptide on gastric motor function and nutrient tolerance in humans

Abstract Pancreatic polypeptide (PP) is known to affect food intake. In this exploratory study, we set out to investigate its supraphysiological effect on food tolerance, gastric accommodation, and emptying. In 12 healthy volunteers, 0, 3, or 10 pmol*kg−1*min−1 PP was administered intravenously (PP0...

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Bibliographic Details
Main Authors: Wout Verbeure, Alessandra Rotondo, Pieter Janssen, Florencia Carbone, Jan Tack
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15002