A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling

Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been introduced into biomolecules. Amber suppression is an...

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Bibliographic Details
Main Authors: Birthe Meineke, Johannes Heimgärtner, Alexander J. Craig, Michael Landreh, Lindon W. K. Moodie, Simon J. Elsässer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.768535/full