SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis

SIRPα maintains macrophage homeostasis by interacting with PTK2B kinase in Mycobacterium tuberculosis infection and through autophagy and necroptosis

Summary: Background: To determine whether SIRPα can be a diagnostic marker of pulmonary tuberculosis (PTB) and the molecular mechanism of SIRPα regulating macrophages to kill Mycobacterium tuberculosis (MTB). Methods: Meta-analysis combined with subsequent qRT-PCR, western-blotting and flow cytomet...

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Bibliographic Details
Main Authors: Di Wang, Yunkai Lin, Feihong Xu, Hui Zhang, Xiaoyan Zhu, Zhen Liu, Yuan Hu, Guanjun Dong, Bingqi Sun, Yanhong Yu, Guoren Ma, Zhigang Tang, Diana Legarda, Adrian Ting, Yuan Liu, Jia Hou, Liwei Dong, Huabao Xiong
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:EBioMedicine
Subjects:
Macrophage
Necroptosis
Autophagy
Immune response
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422004601

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http://www.sciencedirect.com/science/article/pii/S2352396422004601

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