Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice

Expression and Roles of Lynx1, a Modulator of Cholinergic Transmission, in Skeletal Muscles and Neuromuscular Junctions in Mice

Lynx1 is a glycosylphosphatidylinositol (GPI)-linked protein shown to affect synaptic plasticity through modulation of nicotinic acetylcholine receptor (nAChR) subtypes in the brain. Because of this function and structural similarity to α-bungarotoxin, which binds muscle-specific nAChRs with high af...

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Bibliographic Details
Main Authors: Sydney V. Doss, Sébastien Barbat-Artigas, Mikayla Lopes, Bhola Shankar Pradhan, Tomasz J. Prószyński, Richard Robitaille, Gregorio Valdez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
synaptic plasticity
aging
acetylcholine receptor
skeletal muscle
cholinergic transmission
neuromuscular junction
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.838612/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.838612/full

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