Septic macrophages induce T cells immunosuppression in a cell-cell contact manner with the involvement of CR3

Septic macrophages induce T cells immunosuppression in a cell-cell contact manner with the involvement of CR3

Background: In addition to excessive inflammation, immunosuppression has been recognized as a contributing factor to poor prognosis of sepsis. Although it has been reported that T cells can become functionally impaired during sepsis, the underlying mechanisms responsible for this phenomenon remain u...

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Bibliographic Details
Main Authors: Shunwei Huang, Ying Chen, Fangchen Gong, Weiwei Chen, Yanjun Zheng, Bing Zhao, Wen Shi, Zhitao Yang, Hongping Qu, Enqiang Mao, Erzhen Chen
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Sepsis
Macrophages
T cells
Immunosuppression
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023104749

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http://www.sciencedirect.com/science/article/pii/S2405844023104749

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