Assessing the therapeutic response of tumors to hypoxia-targeted prodrugs with an in silico approach
Tumor hypoxia is commonly recognized as a condition stimulating the progress of the aggressive phenotype of tumor cells. Hypoxic tumor cells inhibit the delivery of cytotoxic drugs, causing hypoxic areas to receive insufficient amounts of anticancer agents, which results in adverse treatment respons...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2022-08-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2022511?viewType=HTML |