Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification

Extracellular acidification has been shown to be an important characteristic of invasive tumors, as it promotes invasion and migration but also resistance to treatments. Targeting transporters involved in the regulation of tumor pH constitutes a promising anti-tumor approach, as it would disrupt cel...

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Bibliographic Details
Main Authors: Chloe Buyse, Nicolas Joudiou, Aude Warscotte, Elena Richiardone, Lionel Mignion, Cyril Corbet, Bernard Gallez
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/6/557