Imbalance of laminar-specific excitatory and inhibitory circuits of the orbitofrontal cortex in autism

Imbalance of laminar-specific excitatory and inhibitory circuits of the orbitofrontal cortex in autism

Abstract Background The human orbitofrontal cortex (OFC) is involved in assessing the emotional significance of events and stimuli, emotion-based learning, allocation of attentional resources, and social cognition. Little is known about the structure, connectivity and excitatory/inhibitory circuit i...

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Bibliographic Details
Main Authors: Xuefeng Liu, Julied Bautista, Edward Liu, Basilis Zikopoulos
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Autism
Subjects:
Cortical layers
Myelinated axons
Inhibitory neurons
Calbindin
Parvalbumin
Calretinin
Online Access:http://link.springer.com/article/10.1186/s13229-020-00390-x

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http://link.springer.com/article/10.1186/s13229-020-00390-x

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