Effect of interleukin-1 antagonist on growth of children with colchicine resistant or intolerant FMF

Effect of interleukin-1 antagonist on growth of children with colchicine resistant or intolerant FMF

Abstract Introduction Familial Mediterranean Fever (FMF) is the most common monogentic autoinflammatory disease. FMF results from mutations in MEFV, which lead to a pro-inflammatory state and increased production of Interleukin 1 beta subunit (IL-1b) by myeloid cells. Despite the overall positive re...

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Bibliographic Details
Main Authors: Shiran Pinchevski-Kadir, Maya Gerstein, Oren Pleniceanu, Yonatan Yacobi, Asaf Vivante, Ortal Erez Granat, Shiri Spielman, Rotem Semo Oz, Irit Tirosh
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Pediatric Rheumatology Online Journal
Subjects:
FMF
Anti-IL-1
Growth
Online Access:https://doi.org/10.1186/s12969-022-00784-6

Internet

https://doi.org/10.1186/s12969-022-00784-6

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