CX3CR1 Deficiency Attenuates DNFB-Induced Contact Hypersensitivity through Skewed Polarization towards M2 Phenotype in Macrophages

CX3CR1 Deficiency Attenuates DNFB-Induced Contact Hypersensitivity through Skewed Polarization towards M2 Phenotype in Macrophages

CX3CL1 can function as both an adhesion molecule and a chemokine for CX3CR1<sup>+</sup> cells, such as T cells, monocytes, and NK cells. Recent studies have demonstrated that CX3CL1–CX3CR1 interaction is associated with the development of various inflammatory skin diseases. In this study...

Full description

Bibliographic Details
Main Authors: Sayaka Otobe, Teruyoshi Hisamoto, Tomomitsu Miyagaki, Sohshi Morimura, Hiraku Suga, Makoto Sugaya, Shinichi Sato
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
CX3CR1
contact hypersensitivity
macrophage
tumor necrosis factor-α
interleukin-6
arginase-1
Online Access:https://www.mdpi.com/1422-0067/21/19/7401

Internet

https://www.mdpi.com/1422-0067/21/19/7401

Similar Items